Plasmids for Optogenetics Research

Background

Optogenetics plasmids encode proteins that are controlled by light. Many of these plasmids encode for microbial opsins, which are membrane channels and pores derived from algae and archaebacteria, that can be opened and closed in response to light. These proteins can be expressed in specific neurons, often utilizing viral expression systems, to activate or deactivate these neurons in a precise manner.

One of the first microbial opsins to be adopted as an optogenetic tool is the widely used Channelrhodopsin-2 (ChR2) from Chlamydomonas reinhardtii. ChR2 is a membrane channel that opens in response to blue light and allows cations to flow into the cell. Variants of channelrhodopsin have been engineered or identified to increase the spectral and kinetic properties as well as improve the expression and membrane targeting in host cells. Other microbial opsins, such as the Halorhodopsins, Archaerhodopsins and Leptosphaeria rhodopsins, are pumps that can actively move cations or anions into or out of the cell. When using these opsins as a tool to control neuronal activity, scientists generally attach a fluorescent protein to the opsin in order to track its expression and localization.

Many other types of proteins can also be controlled by light, generally by utilizing a light sensitive protein from cryptochromes, phytochromes, or light-oxygen-voltage-sensing (LOV) proteins. These fusions can then be used as an optical switch to control protein interactions, dimerization, localization or activity of many different types of proteins.

Continue to the tables below to find the best optogenetics plasmids for your experiment. Or see Addgene's Optogenetics Guide for more complete descriptions of the many variants of opsins and other light controlled protein tools.

Interested in more news about optogenetics research? Check out the related posts on Addgene's blog.

Microbial Opsin Plasmids

Addgene has a large collection of optogenetics plasmids derived from microbial opsins that can be used to study neuronal function in various contexts. We also offer ready-to-use AAV preparations of select optogenetics plasmids; these are noted with the viral service icon . Click on different properties to create a custom filtered list of the optogenetics plasmids in Addgene's collection. For a full description (including peak response spectra) of different types of opsins available in this table, see the Glossary in Addgene's Optogenetics Guide.

Activity

• Excitatory
• Inhibitory

Opsin Type

• Channelrhodopsin
• Halorhodopsin
• Leptosphaeria
• Archaerhodopsin
• Other

Reporter FP

• Green
• Red
• Yellow
• Other

Plasmid type

• Mammalian, non-viral
• AAV
• Lentiviral
• Other

Viral Service available 

• Yes

Clear Filters

	Addgene ID	Plasmid Name	Activity	Opsin Variant	Plasmid Type	Reporter	PI
	14750	FCK-Halo-GFP	Inhibitory	Halo	Lentiviral	GFP	Boyden
	15753	pCAGGS-ChR2-Venus	Excitatory	ChR2	Mammalian	Venus	Svoboda
	15814	FCK-ChR2-GFP	Excitatory	ChR2	Lentiviral	GFP	Boyden
	18916	AAV-FLEX-rev-ChR2(H134R)-mCherry	Excitatory	ChR2-H134R	AAV	mCherry	Sternson
	18917	AAV-FLEX-rev-ChR2-tdtomato	Excitatory	ChR2	AAV	tdTomato	Sternson
	20071	pACAGW-ChR2-Venus-AAV	Excitatory	ChR2	AAV	Venus	Svoboda
	20293	pLenti-CaMKIIa-hChR2(C128A)-EYFP-WPRE	Excitatory	SFO	Lentiviral	EYFP	Deisseroth
	20294	pLenti-CaMKIIa-hChR2(C128S)-EYFP-WPRE	Excitatory	SFO	Lentiviral	EYFP	Deisseroth
	20295	pLenti-CaMKIIa-hChR2(C128T)-EYFP-WPRE	Excitatory	SFO	Lentiviral	EYFP	Deisseroth
	20297	pAAV-EF1a-double floxed-hChR2(H134R)-mCherry-WPRE-HGHpA	Excitatory	ChR2-H134R	AAV	mCherry	Deisseroth
	20298	pAAV-EF1a-double floxed-hChR2(H134R)-EYFP-WPRE-HGHpA	Excitatory	ChR2-H134R	AAV	EYFP	Deisseroth
	20938	pcDNA3.1/hChR2(H134R)-mCherry	Excitatory	ChR2-H134R	Mammalian	mCherry	Deisseroth
	20939	pcDNA3.1/hChR2-EYFP	Excitatory	ChR2	Mammalian	EYFP	Deisseroth
	20940	pcDNA3.1/hChR2(H134R)-EYFP	Excitatory	ChR2-H134R	Mammalian	EYFP	Deisseroth
	20942	pLenti-EF1a-hChR2(H134R)-EYFP-WPRE	Excitatory	ChR2-H134R	Lentiviral	EYFP	Deisseroth
	20943	pLenti-CaMKIIa-hChR2(H134R)-mCherry-WPRE	Excitatory	ChR2-H134R	Lentiviral	mCherry	Deisseroth
	20944	pLenti-CaMKIIa-hChR2(H134R)-EYFP-WPRE	Excitatory	ChR2-H134R	Lentiviral	EYFP	Deisseroth
	20945	pLenti-Synapsin-hChR2(H134R)-EYFP-WPRE	Excitatory	ChR2-H134R	Lentiviral	EYFP	Deisseroth
	20946	pLenti-CaMKIIa-eNpHR-EYFP-WPRE	Inhibitory	eNpHR	Lentiviral	EYFP	Deisseroth
	20949	pAAV-double floxed-eNpHR-EYFP-WPRE-pA	Inhibitory	eNpHR	AAV	EYFP	Deisseroth
	20954	pLenti-CaMKIIa-VChR1-EYFP-WPRE	Excitatory	VChR1	Lentiviral	YFP	Deisseroth
	20955	pcDNA3.1/VChR1-EYFP	Excitatory	VChR1	Mammalian	EYFP	Deisseroth
	21484	CHR2-MBD	Excitatory	ChR2	Mammalian	EGFP	Arnold
	22047	ChR2-2A-Halo	Excitatory	ChR2/Halo	Mammalian	GFP/YFP	Boyden
	22051	Fubi-ChR2-GFP	Excitatory	ChR2	Lentiviral	GFP	Boyden
	22217	FCK-Arch-GFP	Inhibitory	Arch	Lentiviral	GFP	Boyden
	22221	FCK-Arch-CFP	Inhibitory	Arch	Lentiviral	CFP	Boyden
	22222	AAV-FLEX-Arch-GFP	Inhibitory	Arch	AAV	GFP	Boyden
	22223	FCK-Mac-GFP	Inhibitory	Mac	Lentiviral	GFP	Boyden
	22224	FCK-ss-Prl-Arch-GFP	Inhibitory	Arch	Lentiviral	GFP	Boyden
	22772	pMH4-SYN-ChR2-tdimer2RFP	Excitatory	ChR2	Mammalian	tdimer2RFP	Oertner
	26057	ChR2-YFP-NavII-III	Excitatory	ChR2	Lentiviral	EYFP	Grubb
	26775	pLenti-hSyn-eNpHR 3.0-EYFP	Inhibitory	eNpHR 3.0	Lentiviral	EYFP	Deisseroth
	26929	AAV-CAG-ChR2-GFP	Excitatory	ChR2	AAV	GFP	Boyden
	26966	pAAV-Ef1a-DIO eNpHR 3.0-EYFP	Inhibitory	eNpHR 3.0	AAV	EYFP	Deisseroth
	26967	pLenti-CaMKIIa-ChETA-EYFP	Excitatory	ChETA	Lentiviral	EYFP	Deisseroth
	26968	pAAV-Ef1a-DIO ChETA-EYFP	Excitatory	ChETA	AAV	EYFP	Deisseroth
	26969	pAAV-CaMKIIa-hChR2(H134R)-EYFP	Excitatory	ChR2-H134R	AAV	EYFP	Deisseroth
	26970	pLenti-CaMKIIa-eNpHR 3.0-EYFP	Inhibitory	eNpHR 3.0	Lentiviral	EYFP	Deisseroth
	26971	pAAV-CaMKIIa-eNpHR 3.0-EYFP	Inhibitory	eNpHR 3.0	AAV	EYFP	Deisseroth
	26972	pAAV-hSyn-eNpHR 3.0-EYFP	Inhibitory	eNpHR 3.0	AAV	EYFP	Deisseroth
	26973	pAAV-hSyn-hChR2(H134R)-EYFP	Excitatory	ChR2-H134R	AAV	EYFP	Deisseroth
	26975	pAAV-CaMKIIa-hChR2(H134R)-mCherry	Excitatory	ChR2-H134R	AAV	mCherry	Deisseroth
	26976	pAAV-hSyn-hChR2(H134R)-mCherry	Excitatory	ChR2-H134R	AAV	mCherry	Deisseroth
	27054	pAAV-GFAP-hChR2(H134R)-EYFP	Excitatory	ChR2-H134R	AAV	EYFP	Deisseroth
	27055	pAAV-GFAP-hChR2(H134R)-mCherry	Excitatory	ChR2-H134R	AAV	mCherry	Deisseroth
	28015	AAV-CAG-hChR2_tdTomato	Excitatory	ChR2	AAV	tdTomato	Svoboda
	28017	AAV-CAG-hChR2-H134R-tdTomato	Excitatory	ChR2-H134R	AAV	tdTomato	Svoboda
	28305	pAAV-FLEX-ArchT-tdTomato	Inhibitory	ArchT	AAV	tdTomato	Boyden
	28307	pAAV-FLEX-ArchT-GFP	Inhibitory	ArchT	AAV	GFP	Boyden
	29777	pAAV-CAG-ArchT-GFP	Inhibitory	ArchT	AAV	GFP	Boyden
	29778	pAAV-CAG-ArchT-tdTomato	Inhibitory	ArchT	AAV	tdTomato	Boyden
	30541	AAV-Flex-rev-oChIEF-tdTomato	Excitatory	ChIEF	AAV	tdTomato	McQuiston
	31177	FCK-ArchT-GFP	Inhibitory	ArchT	Lentiviral	GFP	Boyden
	32646	pSADdeltaG-ChR2-mCherry	Excitatory	ChR2	Rabies	mCherry	Callaway
	32846	pACAGW-oChiEFtdTomato-AAV	Excitatory	ChIEF	AAV	tdTomato	McQuiston
	34616	pJMK004	Inhibitory	Arch D95N	Lentiviral	GFP	Cohen
	34630	Ai27	Excitatory	ChR2-H134R	Mammalian	tdTomato	Zeng
	34880	Ai32	Excitatory	ChR2-H134R	Mammalian	EYFP	Zeng
	34882	Ai35	Inhibitory	Arch	Mammalian	GFP	Zeng
	34884	Ai39	Inhibitory	eNpHR 3.0	Mammalian	EYFP	Zeng
	35497	pAAV-Ef1a-DIO C1V1 (t/t)-TS-EYFP	Excitatory	C1V1	AAV	EYFP	Deisseroth
	35498	pAAV-Ef1a-DIO C1V1 (t/t)-TS-mCherry	Excitatory	C1V1	AAV	mCherry	Deisseroth
	35499	pAAV-CaMKIIa-C1V1 (t/t)-TS-EYFP	Excitatory	C1V1	AAV	EYFP	Deisseroth
	35500	pAAV-CaMKIIa-C1V1 (t/t)-TS-mCherry	Excitatory	C1V1	AAV	mCherry	Deisseroth
	35501	pAAV-CaMKIIa-hChR2(C128S/D156A)-EYFP	Excitatory	SSFO	AAV	EYFP	Deisseroth
	35502	pAAV-CaMKIIa-hChR2(C128S/D156A)-mCherry	Excitatory	SSFO	AAV	mCherry	Deisseroth
	35503	pAAV-Ef1a-DIO hChR2(C128S/D156A)-EYFP	Excitatory	SSFO	AAV	EYFP	Deisseroth
	35504	pAAV-Ef1a-DIO hChR2(C128S/D156A)-mCherry	Excitatory	SSFO	AAV	mCherry	Deisseroth
	35505	pAAV-CaMKIIa-hChR2(E123A)-EYFP	Excitatory	ChETA	AAV	EYFP	Deisseroth
	35506	pAAV-CaMKIIa-hChR2(E123A)-mCherry	Excitatory	ChETA	AAV	mCherry	Deisseroth
	35507	pAAV-Ef1a-DIO hChR2(E123A)-EYFP	Excitatory	ChETA	AAV	EYFP	Deisseroth
	35508	pAAV-Ef1a-DIO hChR2(E123A)-mCherry	Excitatory	ChETA	AAV	mCherry	Deisseroth
	35509	pAAV-Ef1a-DIO hChR2(E123T/T159C)-EYFP	Excitatory	ChETA	AAV	EYFP	Deisseroth
	35510	pAAV-Ef1a-DIO hChR2(E123T/T159C)-mCherry	Excitatory	ChETA	AAV	mCherry	Deisseroth
	35511	pAAV-CaMKIIa-hChR2(E123T/T159C)-EYFP	Excitatory	ChETA	AAV	EYFP	Deisseroth
	35512	pAAV-CaMKIIa-hChR2(E123T/T159C)-mCherry	Excitatory	ChETA	AAV	mCherry	Deisseroth
	35513	pLenti-CaMKIIa-eArchT 3.0-EYFP	Inhibitory	eArch 3.0	Lentiviral	EYFP	Deisseroth
	35514	pLenti-CaMKIIa-eArch 3.0-EYFP	Inhibitory	eArch 3.0	Lentiviral	EYFP	Deisseroth
	35515	pLenti-CaMKIIa-Mac 3.0-EYFP	Inhibitory	eMac 3.0	Lentiviral	EYFP	Deisseroth
	35516	pAAV-CaMKIIa-eArch 3.0-EYFP	Inhibitory	eArch 3.0	AAV	EYFP	Deisseroth
	35519	pLenti-CaMKIIa-C1C2-EYFP	Excitatory	C1C2	Lentiviral	EYFP	Deisseroth
	35520	pLenti-CaMKIIa-C1C2-TS-EYFP	Excitatory	C1C2	Lentiviral	EYFP	Deisseroth
	37082	pAAV-Ef1a-DO-hChR2(H134R)-mCherry-WPRE-pA	Excitatory	ChR2-H134R	AAV	mCherry	Sabatini
	37086	pAAV-Ef1a-DO-ChETA-EYFP-WPRE-pA	Excitatory	ChETA	AAV	EYFP	Sabatini
	37087	pAAV-Ef1a-DO-NpHR3.0-eYFP-WPRE-pA	Inhibitory	NpHR3.0	AAV	EYFP	Sabatini
	37088	pAAV-Ef1a-FAS-NpHR3.0-eYFP-WPRE-pA	Inhibitory	NpHR3.0	AAV	EYFP	Sabatini
	37089	pAAV-Ef1a-FAS-ChETA-TdTomato-WPRE-pA	Excitatory	ChETA	AAV	tdTomato	Sabatini
	37090	pAAV-Ef1a-FAS-hChR2(H134R)-mCherry-WPRE-pA	Excitatory	ChR2-H134R	AAV	mCherry	Sabatini
	37755	pAAV-Ef1a-DIO-ChETA-TdTomato-WPRE-pA	Excitatory	ChETA	AAV	tdTomato	Sabatini
	37756	pAAV-Ef1a-DO-ChETA-TdTomato-WPRE-pA	Excitatory	ChETA	AAV	tdTomato	Sabatini
	37807	pAAV-CamKII-ArchT-GFP	Inhibitory	ArchT	AAV	GFP	Boyden
	37810	pAAV-CAG-Arch-GFP	Inhibitory	Arch	AAV	GFP	Boyden
	41015	hSyn1-FLEX-hChR2-tdtomato	Excitatory	ChR2	AAV	tdTomato	Svoboda
	45188	pLenti-Arch-EEQ	Inhibitory	Arch-EEQ	Lentiviral	EYFP	Schnitzer
	45189	pLenti-Arch-EEN	Inhibitory	Arch-EEN	Lentiviral	EYFP	Schnitzer
	47631	pOTTC469 - pAAV EF1a DIO eNpHR3.0-iRFP	Inhibitory	eNpHR 3.0	AAV	iRFP	Harvey
	47633	pOTTC468 - pAAV EF1a DIO hChR2(H134R)-iRFP	Excitatory	ChR2-H134R	AAV	iRFP	Harvey
	47904	pOTTC352 - pAAV CaMKIIa eNpHR3.0-iRFP	Inhibitory	eNpHR 3.0	AAV	iRFP	Harvey
	47905	pOTTC351 - pAAV CaMKIIa hChR2(H134R)-iRFP	Excitatory	ChR2-H134R	AAV	iRFP	Harvey
	50834	pOTTC292 - pAAV EF1a floxed hChR2(H134R)-EYFP	Excitatory	ChR2-H134R	AAV	EYFP	Harvey
	50954	AAV-ReaChR-citrine	Excitatory	ReaChR	AAV	Citrine	Tsien
	50955	AAV-flex-ReaChR-citrine	Excitatory	ReaChR	AAV	Citrine	Tsien
	50956	pLenti-ReaChR-citrine	Excitatory	ReaChR	Lentiviral	Citrine	Tsien
	50973	AAV-flex-oChIEF-citrine	Excitatory	ChIEF	AAV	Citrine	Tsien
	50974	AAV-oChIEF-citrine	Excitatory	ChIEF	AAV	Citrine	Tsien
	50975	AAV-oChEF-citrine	Excitatory	ChEF	AAV	Citrine	Tsien
	50976	AAV-oChD-citrine	Excitatory	ChD	AAV	Citrine	Tsien
	50977	AAV-oChIEF-tdTomato	Excitatory	ChIEF	AAV	tdTomato	Tsien
	51081	Arch(D95H)-eGFP	Inhibitory	Arch D95H	Lentiviral	EGFP	Cohen
	51092	pAAV-CaMKIIa-oChIEF(E163A/T199C)-P2A-mKate2	Excitatory	ChIEF	AAV	mKate2	Ting
	51093	pAAV-CaMKIIa-oChIEF(E163A/T199C)-P2A-EGFP	Excitatory	oChIEF	AAV	EGFP	Ting
	51094	AAV-EF1a-DIO-oChIEF(E163A/T199C)-P2A-dTomato-WPRE-BGHpA	Excitatory	oChIEF	AAV	tdTomato	Ting
	51095	AAV-EF1a-DIO-ChIEF(E162A/T198C)-P2A-dTomato-WPRE-BGHpA	Excitatory	ChIEF	AAV	tdTomato	Ting
	51110	pAAV-CaMKIIa-eArchT3.0-P2A-EGFP-WPRE-hGHpA	Inhibitory	eArchT3.0	AAV	EGFP	Ting
	51693	DRH313: FCK-CheRiff-eGFP	Excitatory	CheRiff	Lentiviral	EGFP	Cohen
	51697	DRH337: AAV-hsyn-CheRiff-eGFP	Excitatory	CheRiff	AAV	EGFP	Cohen
	52496	pRVdG-4Halo3Y	Inhibitory	eNpHR 3.0	Rabies	EYFP	Wickersham
	52878	pAAV CaMKIIa ChR2 E90R D156N T159C 2A tDimer	Inhibitory	ChR2 E90R D156N T159C	AAV	RFP	Oertner
	55630	pAAV-CaMKIIa-SwiChRca-TS-EYFP	Inhibitory	SwiChRca	AAV	EYFP	Deisseroth
	55631	pAAV-Ef1a-DIO SwiChRca-TS-EYFP	Inhibitory	SwiChRca	AAV	EYFP	Deisseroth
	55639	pAAV-Ef1a-fDIO hChR2(H134R)-EYFP	Excitatory	ChR2-H134R	AAV	EYFP	Deisseroth
	55640	pAAV-Ef1a-dDIO hChR2(H134R)-EYFP	Excitatory	ChR2-H134R	AAV	EYFP	Deisseroth
	55642	pAAV-Ef1a-sCreDIO hChR2(H134R)-EYFP	Excitatory	ChR2-H134R	AAV	EYFP	Deisseroth
	55643	pAAV-Ef1a-vCreDIO hChR2(H134R)-EYFP	Excitatory	ChR2-H134R	AAV	EYFP	Deisseroth
	55644	pAAV-nEF Con/Fon hChR2(H134R)-EYFP	Excitatory	ChR2-H134R	AAV	EYFP	Deisseroth
	55645	pAAV-hSyn Con/Fon hChR2(H134R)-EYFP	Excitatory	ChR2-H134R	AAV	EYFP	Deisseroth
	55646	pAAV-hSyn Con/Foff hChR2(H134R)-EYFP	Excitatory	ChR2-H134R	AAV	EYFP	Deisseroth
	55647	pAAV-nEF Con/Foff hChR2(H134R)-EYFP	Excitatory	ChR2-H134R	AAV	EYFP	Deisseroth
	55648	pAAV-hSyn Coff/Fon hChR2(H134R)-EYFP	Excitatory	ChR2-H134R	AAV	EYFP	Deisseroth
	55649	pAAV-hnEF Coff/Fon hChR2(H134R)-EYFP	Excitatory	ChR2-H134R	AAV	EYFP	Deisseroth
	58487	VV001: WT Arch-3 in pET28b	Inhibitory	Arch	Bacterial	none	Cohen
	58488	VV020: WT Arch-3 - eGFP in pET28b	Inhibitory	Arch	Bacterial	EGFP	Cohen
	58490	VV017: Archaerhodopsin-3 w/ D95Q point mutation fused to eGFP	Inhibitory	Arch D95Q	Lentiviral	EGFP	Cohen
	58510	VV201: ChR2(C128S)-eGFP in fubi	Excitatory	SFO	Lentiviral	EGFP	Cohen
	58512	VV220: CoChR(C108S)-eGFP in fck	Excitatory	SFO	Lentiviral	EGFP	Cohen
	58513	VV221: sdChR(C138S)-TS-eGFP-ER in fck	Excitatory	SFO	Lentiviral	EGFP	Cohen
	58523	VV228: sdChR(C138S E154A)-TS in fck	Excitatory	sdChR	Lentiviral	none	Cohen
	58803	pAAV-CAG-FLEX-Mac-GFP	Inhibitory	Mac	AAV	GFP	Boyden
	58805	pAAV-CaMKII-Chronos-GFP	Excitatory	Chronos	AAV	GFP	Boyden
	58806	pAAV-Syn-ChrimsonR-GFP	Excitatory	ChrimsonR	AAV	GFP	Boyden
	58841	pAAV-Syn-CsChR-GFP	Excitatory	CsChR	AAV	GFP	Boyden
	58849	pAAV-CaMKII-Mac-GFP	Inhibitory	Mac	AAV	GFP	Boyden
	58851	pAAV-EF1a-FLEX-ArchT-GFP	Inhibitory	ArchT	AAV	GFP	Boyden
	58852	pAAV-Syn-FLEX-Mac-GFP	Inhibitory	Mac	AAV	GFP	Boyden
	58853	pAAV-Syn-Mac-GFP	Inhibitory	Mac	AAV	GFP	Boyden
	58880	pAAV-Syn-ChR2(H134R)-GFP	Excitatory	ChR2-H134R	AAV	GFP	Boyden
	58881	pAAV-Syn-ChR2-GFP	Excitatory	ChR2	AAV	GFP	Boyden
	58892	pAAV-GFAP104-ChR2-mCherry	Excitatory	ChR2	AAV	mCherry	Boyden
	59049	FCK-ChrimsonR-GFP	Excitatory	ChrimsonR	Lentiviral	GFP	Boyden
	59056	pCAG-FLEX-rc[Chronos-GFP]	Excitatory	Chronos	Mammalian	GFP	Boyden
	59070	pAAV-Syn-CoChR-GFP	Excitatory	CoChR	AAV	GFP	Boyden
	59137	pCAG-FLEX-fwd[Chrimson-tdT]	Excitatory	Chrimson	Mammalian	tdTomato	Boyden
	59169	pCAG-ChrimsonR-tdT	Excitatory	ChrimsonR	Mammalian	tdTomato	Boyden
	59170	pAAV-Syn-Chronos-GFP	Excitatory	Chronos	AAV	GFP	Boyden
	59171	pAAV-Syn-ChrimsonR-tdT	Excitatory	ChrimsonR	AAV	tdTomato	Boyden
	59325	pRVdG-4ArchT-EGFP	Inhibitory	ArchT	Rabies	EGFP	Wickersham
	59326	pRVdG-4ArchT-mCherry	Inhibitory	ArchT	Rabies	mCherry	Wickersham
	59327	pRVdG-4Halo3-mCherry	Inhibitory	eNpHR 3.0	Rabies	mCherry	Wickersham
	59328	pRVdG-4ChR2-mCherry	Excitatory	ChR2	Rabies	mCherry	Wickersham
	59740	tol2-CAG::ChR2-YFP	Excitatory	ChR2-H134R	Mammalian	YFP	Lieberam
	62718	pAAV-CaMKII-Chrimson-GFP	Excitatory	Chrimson	AAV	GFP	Boyden
	62722	pAAV-Syn-FLEX-rc[Chronos-GFP]	Excitatory	Chronos	AAV	GFP	Boyden
	62723	pAAV-Syn-FLEX-rc[ChrimsonR-tdTomato]	Excitatory	ChrimsonR	AAV	tdTomato	Boyden
	62724	pAAV-Syn-FLEX-rc[CoChR-GFP]	Excitatory	CoChR	AAV	GFP	Boyden
	62725	pAAV-EF1α-FLEX-rc[Chronos-GFP]	Excitatory	Chronos	AAV	GFP	Boyden
	62726	pAAV-Syn-Chronos-tdTomato	Excitatory	Chronos	AAV	tdTomato	Boyden
	62986	pMOS010: pLX304-CheRiff-GFP	Excitatory	CheRiff	Lentiviral	EGFP	Cohen
	63141	pAAV-Syn-ArchT-GFP	Inhibitory	ArchT	AAV	GFP	Boyden
	64035	hSyn-FAS-DO-ReaChR-mCitrine-WPRE	Excitatory	ReaChR	AAV	Citrine	Svoboda
	65012	fck-Jaws-KGC-GFP-ER2	Inhibitory	Jaws	Lentiviral	GFP	Boyden
	65013	fck-Jaws-GFP-ER2	Inhibitory	Jaws	Lentiviral	GFP	Boyden
	65014	pAAV-hsyn-Jaws-KGC-GFP-ER2	Inhibitory	Jaws	AAV	GFP	Boyden
	65015	pAAV-CaMKII-Jaws-KGC-GFP-ER2	Inhibitory	Jaws	AAV	GFP	Boyden
	65016	pAAV-hsyn-Jaws-GFP-ER2	Inhibitory	Jaws	AAV	GFP	Boyden
	65429	AAV phSyn1-RSR-FLEX-ChR2(H134R)-EYFP-WPRE-bGHpA	Excitatory	ChR2-H134R	AAV	EYFP	Zeng
	65454	AAV phSyn1-FSF-FLEX-ChR2(H134R)-EYFP-WPRE-bGHpA	Excitatory	ChR2-H134R	AAV	EYFP	Zeng
	66101	dg263_pENTR_ChrimsonCel	Excitatory	Chrimson	Worm	none	Glauser
	66102	dg264_pENTR_ChronosCel	Excitatory	Chronos	Worm	none	Glauser
	66103	dg265_pENTR_CoChRCel	Excitatory	CoChR	Worm	none	Glauser
	66709	pAAV CaMKIIa iChloC 2A tDimer	Inhibitory	iChloC	AAV	tdimer2	Oertner
	66798	pEIAV-DIO-TLoop-CHR2YFP	Excitatory	ChR2-H134R	Lentiviral	Citrine	Callaway
	67795	pFUGW-hGtACR1-EYFP	Inhibitory	GtACR1	Lentiviral	EYFP	Spudich
	67877	pFUGW-hGtACR2-EYFP	Inhibitory	GtACR2	Lentiviral	EYFP	Spudich
	67958	pcDNA4_ChR2opt_mKATE	Excitatory	ChR2-H134R	Mammalian	mKate	Offenhäusser
	69057	pcDNA3.1_PsChR2_EYFP	Excitatory	PsChR2	Mammalian	EYFP	Spudich
	70111	pLenti-Synapsin-pHoenix-WPRE	Inhibitory	Arch	Lentiviral	mKate2	Rosenmund
	70762	pAAV EF1a DIO iChloC 2A dsRed	Inhibitory	iChloC	AAV	dsRed	Oertner
	72888	pcDNA3.1-CAG-LMO1 (GLuc-ChR2-EYFP)	Excitatory	ChR2	Mammalian	EYFP	Hochgeschwender
	72889	pcDNA3.1-CMV-LMO2 (GLuc-VChR1-EYFP)	Excitatory	VChR1	Mammalian	EYFP	Hochgeschwender
	73465	RabV CVS-N2c(deltaG)-hChR2-YFP	Excitatory	ChR2	Rabies	YFP	Jessell
	73681	N2c(dG)-hChR2-mCherry	Excitatory	ChR2	Rabies	mCherry	Jessell
	75470	pAAV-CAG-FLEXFRT-ChR2(H134R)-mCherry	Excitatory	ChR2-H134R	AAV	mCherry	Cepko
	78174	pAAV-hSyn-FLEX-rc [Jaws-KGC-GFP-ER2]	Inhibitory	Jaws	AAV	GFP	Boyden
	78195	pJL1702	Excitatory	ChR2	Worm	none	Lee
	78196	pJL1703	Excitatory	ChR2	Worm	none	Lee
	79627	pTRE Tight ArchT-GFP	Inhibitory	ArchT	Mammalian	EGFP	Hayashi
	80160	pEIAV-TLoop-Chr2-YFP	Excitatory	ChR2-H134R	Lentiviral	YFP	Callaway
	80902	FCK-Chronos-GFP	Excitatory	Chronos	Lentiviral	GFP	Boyden
	83898	pAAV-mDlx-ChR2-mCherry-Fishell-3	Excitatory	ChR2	AAV	mCherry	Fishell
	84445	pAAV-CAG-FLEX-rc [Jaws-KGC-GFP-ER2]	Inhibitory	Jaws	AAV	GFP	Boyden
	84446	pAAV-CAG-FLEX-rc [Jaws-KGC-tdTomato-ER2]	Inhibitory	Jaws	AAV	tdTomato	Boyden
	84471	pAAV-RAM-d2TTA::TRE-ChR2-WPREpA	Excitatory	ChR2	AAV	EYFP	Lin
	84472	pAAV-RAM-d2TTA::TRE-ArchT-WPREpA	Inhibitory	ArchT	AAV	EGFP	Lin
	84480	pAAV-Syn-FLEX-rc [ChrimsonR-GFP]	Excitatory	ChrimsonR	AAV	GFP	Boyden
	84481	pAAV-Syn-FLEX-rc [Chronos-tdTomato]	Excitatory	Chronos	AAV	tdTomato	Boyden
	84482	pAAV-Syn-FLEX-fd [Chronos-GFP]	Excitatory	Chronos	AAV	GFP	Boyden
	84483	pAAV-Syn-FLEX-fd [ChrimsonR-tdTomato]	Excitatory	ChrimsonR	AAV	tdTomato	Boyden
	84484	pAAV-CAG-FLEX-rc [Chronos-tdTomato]	Excitatory	Chronos	AAV	tdTomato	Boyden
	84485	pAAV-EF1α1.1-FLEX-rc [Chronos-GFP]	Excitatory	Chronos	AAV	GFP	Boyden
	85399	pAAV CAG ChR2 E123T T159C 2A tDimer	Excitatory	ChR2 E123T/T159C	AAV	tDimer	Oertner
	85461	p-mCherry-N1-ChloC	Inhibitory	ChloC	Mammalian	mCherry	Hegemann
	85462	p-mCherry-N1-slowChloC	Inhibitory	slowChloC	Mammalian	mCherry	Hegemann
	85463	p-mCherry-C1-GtACR2	Inhibitory	GtACR2	Mammalian	mCherry	Hegemann
	85464	p-mCherry-C1-GtACR1	Inhibitory	GtACR1	Mammalian	mCherry	Hegemann
	85465	p-mCherry-C1-PsACR1	Inhibitory	PsACR1	Mammalian	mCherry	Hegemann
	86536	pMSCV-ArchT-GFP	Inhibitory	ArchT	Retroviral	GFP	Han
	88844	pFUGW-ZipACR-EYFP	Inhibitory	ZipACR	Lentiviral	EYFP	Spudich
	89256	AAV-syn-ChR2-EYFP-Kv	Excitatory	ChR2	AAV	EYFP	Bolton
	89538	pLenti-PRSX8 eArchT3.0-EYFP	Inhibitory	eArchT 3.0	Lentiviral	EYFP	Stornetta
	89539	pLenti-PRSX8ChR2 (H134R)eYFP	Excitatory	ChR2-H134R	Lentiviral	EYFP	Stornetta
	89570	AAV-syn-ChR2-Kv-P2A-H2b-mRuby2	Excitatory	ChR2	AAV	mRuby2	Bolton
	89876	pAAV-TRE-FLEX-eNpHR-EYFP	Inhibitory	eNpHR	AAV	EYFP	Kwon
	92207	TRE-ChrimsonR-mCherry	Excitatory	ChrimsonR	AAV	mCherry	Ting
	98165	p-mCherry-C1-iC++	Inhibitory	iC++	Mammalian	mCherry	Hegemann
	98166	p-mCherry-C1-Phobos	Inhibitory	Phobos	Mammalian	mCherry	Hegemann
	98167	p-mCherry-C1-Aurora	Inhibitory	Aurora	Mammalian	mCherry	Hegemann
	98168	p-mCherry-C1-iC++_CA	Inhibitory	iC++_CA	Mammalian	mCherry	Hegemann
	98169	p-mCherry-C1-Phobos_CA	Inhibitory	Phobos_CA	Mammalian	mCherry	Hegemann
	98170	p-mCherry-C1-Aurora_CA	Inhibitory	Aurora_CA	Mammalian	mCherry	Hegemann
	98171	p-mCherry-N1-iChloC_CA	Inhibitory	iChloC_CA	Mammalian	mCherry	Hegemann
	98172	p-mCherry-C1-iChR2++	Inhibitory	iChR2++	Mammalian	mCherry	Hegemann
	98173	p-mCherry-C1-iCoChR++	Inhibitory	iCoChR++	Mammalian	mCherry	Hegemann
	98216	AAV2_hSyn_Phobos_Citrine	Inhibitory	Phobos	AAV	Citrine	Wiegert
	98217	AAV2_hSyn_Aurora_Citrine	Inhibitory	Aurora	AAV	Citrine	Wiegert
	98218	AAV2_hSyn_Phobos_CA_Citrine	Inhibitory	Phobos_CA	AAV	Citrine	Wiegert
	98219	AAV2_hSyn_Aurora_CA_Citrine	Inhibitory	Aurora_CA	AAV	Citrine	Wiegert
	98220	AAV2_hSyn_iChloC_CA_Citrine	Inhibitory	iChloC_CA	AAV	Citrine	Wiegert
	99039	pAAV-CamKII-ArchT-GFP (PV2527)	Inhibitory	ArchT	AAV	GFP	Boyden
	99231	pAAV-CaMKII-ChrimsonR-tdTomato	Excitatory	ChrimsonR	AAV	tdTomato	Boyden
	99232	pAAV-CAG-Chronos-GFP	Excitatory	Chronos	AAV	GFP	Boyden
	99233	pAAV-CAG-Jaws-KGC-GFP-ER2	Inhibitory	Jaws	AAV	GFP	Boyden
	99843	Syn-ChR-tdTomato	Excitatory	ChR2-H134R	AAV	tdTomato	Shepherd
	100049	pAAV.hSynap.ChETA(E123T/H134R)-eYFP.WPRE.hGH	Excitatory	ChETA	AAV	EYFP	Deisseroth
	100050	pAAV.CaMKIIa.ChETA(E123T/H134R)-eYFP.WPRE.hGH	Excitatory	ChETA	AAV	EYFP	Deisseroth
	100054	pAAV.CAG.hChR2(H134R)-mCherry.WPRE.SV40	Excitatory	ChR2-H134R	AAV	mCherry	Deisseroth
	100056	pAAV.EF1a.ChR2-YFP.WPRE.hGH	Excitatory	ChR2	AAV	YFP	Deisseroth
	100061	pAAV-Ef1a-DIO C1V1 (t/t)-TS-mCherry (PV2670)	Excitatory	ChR1-VChR1	AAV	mCherry	Deisseroth
	101361	pAAV hSyn1 ChR2 ET-TC 2A tDimer	Excitatory	ChR2 E123T/T159C	AAV	tdimer	Oertner
	102770	pAAV-CamKIIa-ChrimsonR::FusionRed::Kv2.1	Excitatory	ChrimsonR	AAV	FusionRed	Svoboda
	102771	pAAV-CamKIIa-C1V1::FusionRed::Kv2.1	Excitatory	C1V1	AAV	FusionRed	Svoboda
	103137	pcDNA3.1-GcACR_457-EYFP	Inhibitory	GcACR	Mammalian	EYFP	Spudich
	103138	pcDNA3.1-GcACR_145-EYFP	Inhibitory	GcACR	Mammalian	EYFP	Spudich
	103142	pcDNA3.1-GcACR_439-EYFP	Inhibitory	GcACR	Mammalian	EYFP	Spudich
	103143	pcDNA3.1-G1ACR_203-EYFP	Inhibitory	G1ACR	Mammalian	EYFP	Spudich
	103529	pcDNA3.1-PsuACR_433-EYFP	Inhibitory	PsuACR	Mammalian	EYFP	Spudich
	103771	pcDNA3.1-RlACR_477-EYFP	Inhibitory	RlACR	Mammalian	EYFP	Spudich
	103772	pcDNA3.1-RsACR_995-EYFP	Inhibitory	RsACR	Mammalian	EYFP	Spudich
	103773	pcDNA3.1-R1ACR_367-EYFP	Inhibitory	R1ACR	Mammalian	EYFP	Spudich
	103883	pcDNA3.1-R1ACR_877-EYFP	Inhibitory	R1ACR	Mammalian	EYFP	Spudich
	103960	pcDNA3.1-R1ACR_447-EYFP	Inhibitory	R1ACR	Mammalian	EYFP	Spudich
	103961	pcDNA3.1-R1ACR_741-EYFP	Inhibitory	R1ACR	Mammalian	EYFP	Spudich
	103962	pcDNA3.1-R1ACR_799-EYFP	Inhibitory	R1ACR	Mammalian	EYFP	Spudich
	103963	pcDNA3.1-R2ACR_853-EYFP	Inhibitory	R2ACR	Mammalian	EYFP	Spudich
	103964	pcDNA3.1-R2ACR_142-EYFP	Inhibitory	R2ACR	Mammalian	EYFP	Spudich
	103965	pcDNA3.1-C1ACR_887-EYFP	Inhibitory	C1ACR	Mammalian	EYFP	Spudich
	103966	pcDNA3.1-C1ACR_023-EYFP	Inhibitory	C1ACR	Mammalian	EYFP	Spudich
	105446	pCAGGS-Chronos-mRuby2-ST	Excitatory	Chronos	Mammalian	mRuby	Adesnik
	105447	pCAGGS-ChrimsonR-mRuby2-ST	Excitatory	ChrimsonR	Mammalian	mRuby	Adesnik
	105448	pAAV-hSyn-DIO-ChrimsonR-mRuby2-ST	Excitatory	ChrimsonR	AAV	mRuby	Adesnik
	105669	pAAV-CKIIa-stGtACR2-FusionRed	Inhibitory	GtACR2	AAV	FusionRed	Yizhar
	105677	pAAV_hSyn1-SIO-stGtACR2-FusionRed	Inhibitory	GtACR2	AAV	FusionRed	Yizhar
	105678	pAAV_hSyn1-SIO-stGtACR1-FusionRed	Inhibitory	GtACR1	AAV	FusionRed	Yizhar
	105679	pAAV-CKIIa-stGtACR1-FusionRed	Inhibitory	GtACR1	AAV	FusionRed	Yizhar
	105834	AAV-CAG-FLPX-rc [Chronos-tdTomato]	Excitatory	Chronos	AAV	tdTomato	Boyden
	107708	pAAV-hSynapsin- soCoChR-GFP	Excitatory	CoChR	AAV	EGFP	Boyden
	107709	pAAV-EF1alpha-soCoChR-GFP	Excitatory	soCoChR	AAV	GFP	Boyden
	107710	pAAV-CAG-soCoChR-GFP	Excitatory	CoChR	AAV	EGFP	Boyden
	107711	pAAV-CaMKII-soCoChR-GFP	Excitatory	CoChR	AAV	EGFP	Boyden
	107712	pAAV-hSynapsin-FLEX-soCoChR-GFP	Excitatory	CoChR	AAV	EGFP	Boyden
	107713	pAAV-hSyn-soCoChR-mCardinal	Excitatory	CoChR	AAV	mCardinal	Boyden
	107714	pAAV-EF1alpha-soCoChR-tdTomato	Excitatory	CoChR	AAV	tdtomato	Boyden
	107745	pmec-4::Chrimson::SL2::mCherry::unc-54	Excitatory	Chrimson	Worm	mCherry	Leifer
	108273	pAAV-EF1α1.1-FLEX-rc [ChrimsonR-GFP]	Excitatory	ChrimsonR	AAV	EGFP	Boyden
	108274	pAAV-EF1α1.1-FLEX-rc [Jaws-KGC-GFP-ER2]	Inhibitory	Jaws	AAV	EGFP	Boyden
	108902	pCAG-ChroME-mRuby2-ST	Excitatory	ChroME	Mammalian	mRuby2	Adesnik
	108912	pAAV-CAG-DIO-ChroME-ST-P2A-H2B-mRuby3	Excitatory	ChroME	AAV	mRuby3	Adesnik
	108960	pCAG-H2B-mRuby3-IRES-eGtACR1-ST	Inhibitory	GtACR1	Mammalian	mRuby3	Adesnik
	109048	pAAV-CAG-DIO-NLS-mRuby3-IRES-eGtACR1-ST	Inhibitory	GtACR1	AAV	mRuby3	Adesnik
	109124	pCAG-C1V1-TT-mRuby2-ST	Excitatory	C1V1	Mammalian	mRuby2	Adesnik
	109125	pCAG-ChR2-mRuby2-ST	Excitatory	ChR2	Mammalian	mRuby2	Adesnik
	109126	pCAG-ChETA-mRuby2-ST	Excitatory	ChETA	Mammalian	mRuby2	Adesnik
	109127	pCAG-ChroME(F243Y)-mRuby2-ST	Excitatory	ChroME(F243Y)	Mammalian	mRuby2	Adesnik
	109128	pCAG-ChroME(S273A)-mRuby2-ST	Excitatory	ChroME(S273A)	Mammalian	mRuby2	Adesnik
	109129	pCAG-Chronos(M140T)-mRuby2-ST	Excitatory	Chronos(M140T)	Mammalian	mRuby2	Adesnik
	109130	pCAG-CsChR-mRuby2-ST	Excitatory	CsChR	Mammalian	mRuby2	Adesnik
	109131	pCAG-CoChR-mRuby2-ST	Excitatory	CoChR	Mammalian	mRuby2	Adesnik
	109132	pCAG-eiC++-mRuby2-ST	Inhibitory	iC++	Mammalian	mRuby2	Adesnik
	109133	pCAG-ePsuACR-mRuby2-ST	Inhibitory	PsuAcR	Mammalian	mRuby2	Adesnik
	109134	pCAG-eNpHR3.0-mRuby2-ST	Inhibitory	eNpHR3.0	Mammalian	mRuby2	Adesnik
	109135	pCAG-eArch3.0-mRuby2-ST	Inhibitory	eArch3.0	Mammalian	mRuby2	Adesnik
	109136	pCAG-eGtACR1-mRuby2-ST	Inhibitory	GtACR1	Mammalian	mRuby2	Adesnik
	110337	pAAV-TRE-FLEX-ChR2-YFP	Excitatory	ChR2	AAV	YFP	Kwon
	111075	pFUGW-RapACR-EYFP	Inhibitory	RapACR	Lentiviral	YFP	Spudich
	111076	pcDNA3.1-PsuACR_353-EYFP	Inhibitory	PsuAcR	Mammalian	EYFP	Spudich
	111077	pcDNA3.1-RaACR_687-EYFP	Inhibitory	RaACR	Mammalian	EYFP	Spudich
	111078	pcDNA3.1-RlACR_497-EYFP	Inhibitory	RlACR	Mammalian	EYFP	Spudich
	111079	pcDNA3.1-R1ACR_653-EYFP	Inhibitory	R1ACR_653	Mammalian	EYFP	Spudich
	111080	pcDNA3.1-R1ACR_6367-EYFP	Inhibitory	R1ACR	Mammalian	EYFP	Spudich
	111386	pAAV-hSyn-DIO {ChETA}on-WPRE	Excitatory	ChETA	AAV	none	Kepecs
	111387	pAAV-hSyn-DIO {mCAR}off-{ChETA}on-WPRE	Excitatory	ChETA	AAV	none	Kepecs
	111388	pAAV-hSyn-DIO {hCAR}off-{ChETA}on-WPRE	Excitatory	ChETA	AAV	none	Kepecs
	111389	pAAV-hSyn-DIO {ChETA-mRuby2}on-W3SL	Excitatory	ChETA	AAV	mRuby2	Kepecs
	111390	pAAV-hSyn-DIO {mCAR}off-{ChETA-mRuby2}on-W3SL	Excitatory	ChETA	AAV	mRuby2	Kepecs
	111391	pAAV-hSyn-DIO {hCAR}off-{ChETA-mRuby2}on-W3SL	Excitatory	ChETA	AAV	mRuby2	Kepecs
	111392	pAAV-hSyn-DIO {hCAR}off-{ChETA-EYFP}on-W3SL	Excitatory	ChETA	AAV	EYFP	Kepecs
	111544	20XUAS IVS CsChrimson tdtomato_tr	Excitatory	Chrimson	Fly	tdTomato	Jayaraman
	111545	5XUAS IVS CsChrimson tdtomato_tr	Excitatory	Chrimson	Fly	tdTomato	Jayaraman
	111546	20XUAS IVS ChrimsonR mCherry_tr	Excitatory	ChrimsonR	Fly	mCherry	Jayaraman
	111547	10XUAS IVS ChrimsonR mCherry_tr	Excitatory	ChrimsonR	Fly	mCherry	Jayaraman
	111548	13XLexAop2 IVS ChrimsonR mCherry_tr	Excitatory	ChrimsonR	Fly	mCherry	Jayaraman
	111549	20XUAS IVS Jaws mCherry_tr	Inhibitory	Jaws	Fly	mCherry	Jayaraman
	111550	10XUAS IVS Jaws mCherry_tr	Inhibitory	Jaws	Fly	mCherry	Jayaraman
	111551	13XLexAop2 IVS Jaws mCherry_tr	Inhibitory	Jaws	Fly	mCherry	Jayaraman
	111552	20XUAS IVS Jaws mVenus_tr	Inhibitory	Jaws	Fly	mVenus	Jayaraman
	111553	10XUAS IVS Jaws mVenus_tr	Inhibitory	Jaws	Fly	mVenus	Jayaraman
	112496	pZac2.1 GfaABC1D ChR2(H134R) mCherry SV40	Excitatory	ChR2-H134R	AAV	mCherry	Khakh
	114099	pAAV-hSyn-LMO3 (sbGLuc-VChR1-EYFP)	Excitatory	VChR1	AAV	EYFP	Hochgeschwender
	114100	pAAV-hSyn-iLMO (slGLuc-Mac-EYFP)	Inhibitory	Mac	AAV	EYFP	Hochgeschwender
	114101	pAAV-hSyn-LMO4 (GLucM23-VChR1-EYFP)	Excitatory	VChR1	AAV	EYFP	Hochgeschwender
	114103	pAAV-Hb9-LMO3 (sbGLuc-VChR1-EYFP)	Excitatory	VChR1	AAV	EYFP	Hochgeschwender
	114104	pAAV-CAG-LMO3 (sbGLuc-VChR1-EYFP)	Excitatory	VChR1	AAV	EYFP	Hochgeschwender
	114105	pAAV-EFIa-DIO-LMO3 (sbGLuc-VChR1-EYFP)	Excitatory	VChR1	AAV	EYFP	Hochgeschwender
	114106	pAAV-hSyn-sbGLuc-ChR2(CS/DA)-EYFP	Excitatory	ChR2(CS/DA)	AAV	EYFP	Hochgeschwender
	114108	pAAV-hSyn-sbGLuc-CheRiff-EGFP	Excitatory	CheRiff	AAV	EGFP	Hochgeschwender
	114111	pcDNA3.1-CAG-sbGLuc-hGtARC2-EYFP	Inhibitory	GtARC2	Mammalian	EYFP	Hochgeschwender
	114112	pcDNA3.1-CAG-NanoLuc-VChR1-EYFP	Excitatory	VChR1	Mammalian	EYFP	Hochgeschwender
	114216	AAV-CamKIIa-ChR2-EGFP	Excitatory	ChR2	AAV	EGFP	Han
	114367	pCAG-hChR2(H134R)-EYFP	Excitatory	ChR2-H134R	Mammalian	EYFP	Xue
	114368	pAAV-EF1α-DIO-ReaChR-P2A-dTomato	Excitatory	ReaChR	AAV	dtomato	Xue
	114369	pAAV-EF1α-FRT-FLEX-GtACR2-EYFP	Inhibitory	GtACR2	AAV	EYFP	Xue
	114370	pAAV-EF1α-FRT-FLEX-GtACR1-EYFP	Inhibitory	GtACR1	AAV	EYFP	Xue
	114371	pAAV-EF1α-FRT-FLEX-GtACR2-EYFP-MBD	Inhibitory	GtACR2	AAV	EYFP	Xue
	114372	pAAV-EF1α-FRT-FLEX-GtACR2-EYFP-Nlgn1C	Inhibitory	GtACR2	AAV	EYFP	Xue
	114373	pAAV-EF1α-FRT-FLEX-GtACR2-EYFP-Kv4.2LL	Inhibitory	GtACR2	AAV	EYFP	Xue
	114374	pAAV-EF1α-FRT-FLEX-GtACR2-EYFP-TlcnC	Inhibitory	GtACR2	AAV	EYFP	Xue
	114375	pAAV-EF1α-FRT-FLEX-GtACR2-EYFP-Kv2.1C	Inhibitory	GtACR2	AAV	EYFP	Xue
	114376	pAAV-EF1α-FRT-FLEX-GtACR2-EYFP-Kv2.1C-TlcnC	Inhibitory	GtACR2	AAV	EYFP	Xue
	114377	pAAV-EF1α-FRT-FLEX-GtACR2-EYFP-Kv2.1C-linker-TlcnC	Inhibitory	GtACR2	AAV	EYFP	Xue
	114378	pAAV-EF1α-FRT-FLEX-GtACR2-KA2N-EGFP	Inhibitory	GtACR2	AAV	EGFP	Xue
	114431	Ai167 (TIT2L-ChrimsonR-tdT-ICL-tTA2) targeting vector	Excitatory	ChrimsonR	Mammalian	tdTomato	Zeng
	115337	pEYFP-N1-eKR2	Inhibitory	eKR2	Mammalian	EYFP	Hegemann
	117419	pPD_Psra-6::ChR2(H134R)::mCherry	Excitatory	ChR2-H134R	Worm	mCherry	Mitani
	117420	pPD_Pinx-1::ChR2(H134R)::mCherry	Excitatory	ChR2-H134R	Worm	mCherry	Mitani
	118276	pAAV-CamKII-GFP-P2A-bReaches-minWPRE	Excitatory	bReaChES	AAV	EGFP	Schmitz
	118279	pAAV-EF1a-SwitchON_mRubyNLS-hChR2(H134R)-EYFP-NO_WPRE	Excitatory	ChR2-H134R	AAV	EYFP	Schmitz
	118295	AAV-CAG-FLPX-rc [ChrimsonR-GFP]	Excitatory	ChrimsonR	AAV	GFP	Boyden
	119195	pFUGW-RapACR_T111C-EYFP	Inhibitory	RapACR	Lentiviral	EYFP	Spudich
	119196	pFUGW-GtACR1_C102A-EYFP	Inhibitory	GtACR1	Lentiviral	EYFP	Spudich
	119197	pcDNA3.1_RapACR_T111C_N248Q-EYFP	Inhibitory	RapACR	Mammalian	EYFP	Spudich
	119298	AAV-CAG-FLInChR-mVenus	Inhibitory	FLInChR	AAV	mVenus	Karpova
	121542	peAAV-CKII(0.4)-Chronos_eGFP_GP2A_nls_mScarlet	Excitatory	Chronos	AAV	EGFP	Prigge
	121543	pAAV-Dlx5/6-Chronos-eGFP-p2a-nls-mScarlet	Excitatory	Chronos	AAV	EGFP	Prigge
	122063	pAAV-EF1α1.1-ChrimsonR-GFP	Excitatory	ChrimsonR	AAV	EGFP	Boyden
	122064	pAAV-EF1α1.1-ChrimsonR-tdTomato	Excitatory	ChrimsonR	AAV	tdTomato	Boyden
	122098	pAAV-EF1α1.1-Chronos-GFP	Excitatory	Chronos	AAV	GFP	Boyden
	122099	pAAV-EF1α1.1-Chronos-tdTomato	Excitatory	Chronos	AAV	tdTomato	Boyden
	122102	pAAV-EF1α1.1-FLPX-rc [Chronos-GFP]	Excitatory	Chronos	AAV	GFP	Boyden
	122103	AAV-EF1α1.1-FLPX-rc [Chronos-tdTomato]	Excitatory	Chronos	AAV	tdTomato	Boyden
	123312	pcDNA3.1-ArchT-BFP2-TSERex	Inhibitory	ArchT	Mammalian	BFP2	Li
	123607	pAAV-Syn-FLEX-rc [ArchT-tdTomato]	Inhibitory	ArchT	AAV	tdTomato	Boyden
	124231	pTol1-UAS:ChrimsonR-tdTomato	Excitatory	ChrimsonR	Zebrafish	tdTomato	Bianco
	124232	pTol1-UAS:Chronos-tdTomato	Excitatory	Chronos	Zebrafish	tdTomato	Bianco
	124233	pTol1-UAS:CoChR-tdTomato	Excitatory	CoChR	Zebrafish	tdTomato	Bianco
	124235	pTol1-UAS:GtACR1-tdTomato	Inhibitory	GtACR1	Zebrafish	tdTomato	Bianco
	124236	pTol1-UAS:GtACR2-tdTomato	Inhibitory	GtACR2	Zebrafish	tdTomato	Bianco
	124237	pTol1-UAS:ChR2(H134R)-tdTomato	Excitatory	ChR2-H134R	Zebrafish	tdTomato	Bianco
	124603	pAAV-EF1a-DIO-ChrimsonR-mRuby2-KV2.1-WPRE-SV40	Excitatory	ChrimsonR	AAV	mRuby2	Harvey
	124604	pAAV-EF1a-DIO-C1V1(t/t)-mRuby2-KV2.1-WPRE-SV40	Excitatory	C1V1	AAV	Citrine	Harvey
	124640	pAAV-EF1a-FDIO-ArchT-GFP	Inhibitory	ArchT	AAV	GFP	Dupret
	124650	pAAV-CamKIIa-C1V1(t/t)-mScarlet-KV2.1	Excitatory	C1V1	AAV	mScarlet	Harvey
	124651	pAAV-CamKIIa-ChrimsonR-mScarlet-KV2.1	Excitatory	ChrimsonR	AAV	mScarlet	Harvey
	124793	pcDNA3.1-Mac-BFP2-TSERex	Inhibitory	Mac	Mammalian	BFP2	Li
	125255	plenti2-EF1a-ChR2-EYFP-WRPE	Excitatory	ChR2	Lentiviral	EYFP	Kamm
	125256	pLEX307-EF1a-ChR2[H134R]-mCherry-Puro-WPRE	Excitatory	ChR2-H134R	Lentiviral	mCherry	Kamm
	125712	pAAV-CaMKIIa(0.4)-eOPN3-mScarlet-WPRE	Inhibitory	eOPN3	AAV	mScarlet	Yizhar
	125713	pAAV-hSyn1-SIO-eOPN3-mScarlet-WPRE	Inhibitory	eOPN3	AAV	mScarlet	Yizhar
	126080	pAAV-Ef1a-sCreDIO hChR2(H134R)-eYFP 2.0	Excitatory	ChR2-H134R	AAV	EYFP	Deisseroth
	126081	pAAV-Ef1a-vCreDIO hChR2(H134R)-eYFP 2.0	Excitatory	ChR2-H134R	AAV	EYFP	Deisseroth
	126513	p-mCherry-C1-MerMAID1	Inhibitory	MerMAID1	Mammalian	mCherry	Hegemann
	126514	p-mCherry-C1-MerMAID2	Inhibitory	MerMAID2	Mammalian	mCherry	Hegemann
	126515	p-mCherry-C1-MerMAID3	Inhibitory	MerMAID3	Mammalian	mCherry	Hegemann
	126516	p-mCherry-C1-MerMAID4	Inhibitory	MerMAID4	Mammalian	mCherry	Hegemann
	126517	p-mCherry-C1-MerMAID5	Inhibitory	MerMAID5	Mammalian	mCherry	Hegemann
	126518	p-mCherry-C1-MerMAID6	Inhibitory	MerMAID6	Mammalian	mCherry	Hegemann
	126519	p-mCherry-C1-MerMAID7	Inhibitory	MerMAID7	Mammalian	mCherry	Hegemann
	126520	p-AAV2-hSyn-MerMAID1-Citrine	Inhibitory	MerMAID1	AAV	Citrine	Hegemann
	126521	p-AAV2-hSyn-MerMAID6-Citrine	Inhibitory	MerMAID6	AAV	Citrine	Hegemann
	127090	pAAV-CAG-DIO-ChR2(H134R)-eYFP	Excitatory	ChR2-H134R	AAV	EYFP	Gradinaru
	127237	pAAV-hSyn-ChRger2-TS-EYFP	Excitatory	ChRger2	AAV	EYFP	Gradinaru
	127238	pAAV-CaMKIIa-ChRger2-TS-EYFP	Excitatory	ChRger2	AAV	EYFP	Gradinaru
	127239	pAAV-CAG-DIO(ChRger2-TS-YFP)	Excitatory	ChRger2	AAV	EYFP	Gradinaru
	127240	pAAV-hSyn-ChRger3-TS-EYFP	Excitatory	ChRger3	AAV	EYFP	Gradinaru
	127241	pAAV-CaMKIIa-ChRger3-TS-EYFP	Excitatory	ChRger3	AAV	EYFP	Gradinaru
	127242	pAAV-CAG-DIO(ChRger3-TS-YFP)	Excitatory	ChRger3	AAV	EYFP	Gradinaru
	127243	pAAV-hSyn-ChRger1-TS-EYFP	Excitatory	ChRger1	AAV	EYFP	Gradinaru
	127244	pAAV-CaMKIIa-ChRger1-TS-EYFP	Excitatory	ChRger1	AAV	EYFP	Gradinaru
	127245	pAAV-CAG-DIO(ChRger1-TS-YFP)	Excitatory	ChRger1	AAV	EYFP	Gradinaru
	128587	AAV-EF1α1.1-FLPX-rc [ChrimsonR-tdTomato]	Excitatory	ChrimsonR	AAV	tdTomato	Boyden
	128588	AAV-EF1α1.1-FLPX-rc [ChrimsonR-GFP]	Excitatory	ChrimsonR	AAV	GFP	Boyden
	128589	AAV-Syn-FLPX-rc [ChrimsonR-tdTomato]	Excitatory	ChrimsonR	AAV	tdTomato	Boyden
	129393	pAAV-CaMKII-STChRger2-TS-EYFP	Excitatory	ChRger2	AAV	EYFP	Gradinaru
	129394	pAAV-CAG-DIO-(STChRger2-TS-EYFP)	Excitatory	ChRger2	AAV	EYFP	Gradinaru
	129395	pAAV-hSyn-STChRger2-TS-EYFP	Excitatory	ChRger2	AAV	EYFP	Gradinaru
	129432	EF1a CHR2 mCherry WPRE	Excitatory	ChR2	Lentiviral	mCherry	Laur
	130909	AAV-CAG-FLPX-rc [ChrimsonR-tdTomato]	Excitatory	ChrimsonR	AAV	tdTomato	Boyden
	130988	pAAV-CaMKIIa-ChRmine-eYFP-WPRE	Excitatory	Chrmine	AAV	EYFP	Deisseroth
	130990	pAAV-CaMKIIa-ChRmine-mScarlet-WPRE	Excitatory	Chrmine	AAV	mscarlet	Deisseroth
	130992	pAAV-hSyn-ChRmine-eYFP-WPRE	Excitatory	Chrmine	AAV	EYFP	Deisseroth
	130994	pAAV-hSyn-ChRmine-mScarlet-WPRE	Excitatory	Chrmine	AAV	mScarlet	Deisseroth
	130996	pAAV-Ef1a-DIO ChRmine-eYFP-WPRE	Excitatory	Chrmine	AAV	EYFP	Deisseroth
	130998	pAAV-Ef1a-DIO-ChRmine-mScarlet-WPRE	Excitatory	Chrmine	AAV	mScarlet	Deisseroth
	131004	pAAV-hSyn-GCaMP 6m-p2A-ChRmine-Kv2.1-WPRE	Excitatory	ChRmine	AAV	GCaMP6m	Deisseroth
	135176	pAAV-TRE-flex-ChR2 (E123T/T159C)-EYFP	Excitatory	ChR2 E123T/T159C	AAV	EYFP	Yamamori
	135319	flex-ChrimsonR-EYFP-Kv	Excitatory	ChrimsonR	AAV	EYFP	Zeng
	135413	LZF1827 pAAV_hSyn-Flp-off-Cre-on-stGtACR2-CFP	Inhibitory	GtACR2	AAV	CFP	Cohen
	135633	pAAV-S5E2-C1V1-eYFP	Excitatory	C1V1	AAV	EYFP	Dimidschstein
	135634	pAAV-S5E2-ChR2-mCherry	Excitatory	ChR2	AAV	mCherry	Dimidschstein
	135765	UB061 (FCK-stGtACR2-fusionRed)	Inhibitory	GtACR2	Lentiviral	fusionRed	Cohen
	136636	HT041_FCMV_CheRiff_CFP	Excitatory	CheRiff	AAV	CFP	Cohen
	136916	pAAV-hSyn-DFO-ChR2(H134R)-EYFP-WPRE	Excitatory	ChR2-H134R	AAV	EYFP	Yizhar
	137139	pAAV-nEF-Con/Fon-ChR2(ET/TC)-EYFP	Excitatory	ChR2 E123T/T159C	AAV	EYFP	Deisseroth
	137140	pAAV-nEF-Con/Foff 2.0-ChR2(ET/TC)-EYFP	Excitatory	ChR2 E123T/T159C	AAV	EYFP	Deisseroth
	137141	pAAV-nEF-Coff/Fon-ChR2(ET/TC)-EYFP	Excitatory	ChR2 E123T/T159C	AAV	EYFP	Deisseroth
	137142	pAAV-nEF-Con/Fon-ChR2-mCherry	Excitatory	ChR2	AAV	mCherry	Deisseroth
	137143	pAAV-nEF-Con/Foff 2.0-ChR2-mCherry	Excitatory	ChR2	AAV	mCherry	Deisseroth
	137144	pAAV-nEF-Coff/Fon-ChR2-mCherry	Excitatory	ChR2	AAV	mCherry	Deisseroth
	137145	pAAV-nEF-Con/Fon-bREACHes-EYFP	Excitatory	bReaChES	AAV	EYFP	Deisseroth
	137146	pAAV-nEF-Con/Foff 2.0-bREACHes-EYFP	Excitatory	bReaChES	AAV	EYFP	Deisseroth
	137147	pAAV-nEF-Coff/Fon-bREACHes-EYFP	Excitatory	bReaChES	AAV	EYFP	Deisseroth
	137148	pAAV-nEF-Con/Fon-Arch3.3-p2a-EYFP	Inhibitory	Arch3.3	AAV	EYFP	Deisseroth
	137149	pAAV-nEF-Con/Foff 2.0-Arch3.3-EYFP	Inhibitory	Arch3.3	AAV	EYFP	Deisseroth
	137150	pAAV-nEF-Coff/Fon-Arch3.3-p2a-EYFP	Inhibitory	NpHR3.3	AAV	EYFP	Deisseroth
	137151	pAAV-nEF-NpHR3.3-EYFP	Inhibitory	NpHR3.3	AAV	EYFP	Deisseroth
	137152	pAAV-nEF-Con/Fon-NpHR3.3-EYFP	Inhibitory	NpHR3.3	AAV	EYFP	Deisseroth
	137153	pAAV-nEF-Con/Foff 2.0-NpHR3.3-EYFP	Inhibitory	NpHR3.3	AAV	EYFP	Deisseroth
	137154	pAAV-nEF-Coff/Fon-NpHR3.3-EYFP	Inhibitory	NpHR3.3	AAV	EYFP	Deisseroth
	137155	pAAV-nEF-Con/Fon-iC++-EYFP	Inhibitory	iC++	AAV	EYFP	Deisseroth
	137156	pAAV-nEF-Con/Foff 2.0-iC++-EYFP	Inhibitory	iC++	AAV	EYFP	Deisseroth
	137157	pAAV-nEF-Coff/Fon-iC++-EYFP	Inhibitory	iC++	AAV	EYFP	Deisseroth
	137158	pAAV-nEF-ChRmine-mScarlet	Excitatory	ChRmine	AAV	mScarlet	Deisseroth
	137159	pAAV-nEF-Con/Fon-ChRmine-oScarlet	Excitatory	ChRmine	AAV	oScarlet	Deisseroth
	137160	pAAV-nEF-Coff/Fon-ChRmine-oScarlet	Excitatory	ChRmine	AAV	oScarlet	Deisseroth
	137161	pAAV-nEF-Con/Foff 2.0-ChRmine-oScarlet	Excitatory	ChRmine	AAV	oScarlet	Deisseroth
	137163	pAAV-nEF-Con/Foff 2.0-ChR2-EYFP	Excitatory	ChR2	AAV	EYFP	Deisseroth
	139283	pAAV-EF1a-DIO-hChR2(H134R)-P2A-EYFP	Excitatory	ChR2-H134R	AAV	EYFP	Xue
	149690	pAAV-hSyn-Chronos-mT-Sapphire	Excitatory	Chronos	AAV	Sapphire	Malenka
	149691	pAAV-hSyn-ChrimsonR-LSSmOrange	Excitatory	ChrimsonR	AAV	LSSmOrange	Malenka
	149692	pAAV-hSyn-Chronos-mT-Sapphire-NRN	Excitatory	ChrimsonR	AAV	LSSmOrange	Malenka
	149693	pAAV-hSyn-ChrimsonR-LSSmOrange-NRN	Excitatory	ChrimsonR	AAV	LSSmOrange	Malenka
	153029	vPyACR_2164382	Inhibitory	PyACR	Mammalian	EYFP	Hegemann
	153030	vPyACR_21821	Inhibitory	PyACR	Mammalian	EYFP	Hegemann
	153031	PymeACR1	Inhibitory	PymeACR1	Mammalian	mCherry	Hegemann
	153032	Py2087ACR1	Inhibitory	Py2087ACR1	Mammalian	mCherry	Hegemann
	153434	pAAV-E11-ChR2GFP2x	Excitatory	ChR2-H134R	AAV	EGFP	Dimidschstein
	153435	pAAV-E14-ChR2GFP2x	Excitatory	ChR2-H134R	AAV	EGFP	Dimidschstein
	153436	pAAV-E22-ChR2GFP2x	Excitatory	ChR2-H134R	AAV	EGFP	Dimidschstein
	153437	pAAV-E29-ChR2GFP2x	Excitatory	ChR2-H134R	AAV	EGFP	Dimidschstein
	153534	AAV-CaMKII-Jaws-KGC-tdTomato-ER2	Inhibitory	Jaws	AAV	tdTomato	Boyden
	153535	AAV-Syn-Jaws-KGC-tdTomato-ER2	Inhibitory	Jaws	AAV	tdTomato	Boyden
	153536	pAAV-Syn-FLEX-rc [Jaws-KGC-tdTomato-ER2]	Inhibitory	Jaws	AAV	tdTomato	Boyden
	153537	pAAV-EF1α1.1-Jaws-KGC-GFP-ER2	Inhibitory	Jaws	AAV	EGFP	Boyden
	163037	TRE:mCherry-p2a- bReaChES	Excitatory	bReaChES	Mammalian	mCherry	Ting
	163044	pMOS010: CheRiff-eGFP channelrhodopsin (plasma membrane)	Excitatory	CheRiff	Lentiviral	EGFP	Cohen
	163063	pMOS010E: Entry vector for: CheRiff-eGFP channelrhodopsin (plasma membrane)	Excitatory	CheRiff	Other	EGFP	Cohen
	163629	p10xQUAS-CsChrimson	Excitatory	Chrimson	Fly	mVenus	Potter
	166600	pAAV-TRE-DIO-ChR2-TdTomato	Excitatory	ChR2	AAV	tdTomato	Myers
	166604	pAAV-TRE-DIO-SwiChR-eYFP	Inhibitory	SwiChR	AAV	EYFP	Myers
	166610	pAAV-TRE-DIO-ChR2-TdTomato (Cre-OFF)	Excitatory	ChR2	AAV	tdTomato	Myers
	170160	pCAG-ChroME2f-mRuby2-ST	Excitatory	ChroME2f	Mammalian	mRuby3	Adesnik
	170161	pAAV-hSyn-DIO-ChroME-ST-P2A-H2B-mRuby3	Excitatory	ChroME	AAV	mRuby3	Adesnik
	170163	pAAV-CAG-DIO-ChroME2s-ST-P2A-H2B-mRuby3	Excitatory	ChroME2s	AAV	mRuby3	Adesnik
	170175	pAAV-TRE-ChroME2f-ST-P2A-NLS-mRuby3	Excitatory	ChroME2f	AAV	mRuby3	Adesnik
	170177	pAAV-TRE-ChroME2s-ST-P2A-NLS-mRuby3	Excitatory	ChroME2s	AAV	mRuby3	Adesnik
	170845	pAAV-VTKD2-ChR2-mCherry	Excitatory	ChR2	AAV	mCherry	Dimidschstein
	171027	pAAV-Ef1a-fDIO-ChrimsonR-tdTomato	Excitatory	ChrimsonR	AAV	tdTomato	Jensen
	171150	pAAV-CAG-DIO-ChroME2f-ST-P2A-H2B-mRuby3	Excitatory	ChroME2f	AAV	mRuby3	Adesnik
	171158	pCAG-ChroMD-mRuby2-ST	Excitatory	ChroMD	Mammalian	mRuby2	Adesnik

Currently, no available plasmids.

Optical Switch Plasmids

Browse, sort, or search the table below for plasmids that use light to control a protein or cellular activity. For a full description (including peak response spectra) of different domains used in these plasmids, see the Glossary in Addgene's Optogenetics Guide.